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Dr. No
- First appearance of Sean Connery as James Bond
- First appearance of Bernard Lee as 'M'
- First appearance of Lois Maxwell as Ms. Moneypenny
- First time Bond utters the words "Bond. James Bond"
- First appearance of Major Boothroyd (Later known as Q)
- First appearance of Eunich Gayson as Sylvia Trench
- First appearance of Felix Leiter character
- First and last appearance of Bond's Beretta
- First time Bond sweats
- First time Bond's apartment is seen
- First time Bond uses the Walther PPK
- Bond's first on screen mission
- First mention of SPECTRE (Special Executive for Counterintelligence, Terrorism, Revenge, Extortion)
- Bond's first interracial romance (Ms. Taro is Asian)
- First time Bond shoots someone in cold blood (Professor Dent)
- First mention of the space program
- First gunbarrel opening
- The first time Bond throws his hat onto a hatrack when entering M's outer office
- First mention of a vodka martini
- First time 007 drives an American car (1957 Chevrolet Bel Air convertible)
- First time Bond sings
- First time Bond plays cards
- First time Bond is seen smoking
- First time Q is refered to as Quartermaster
- First time Universal Exports is referenced
- First time Bond is captured
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